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Both are zinc oxide diaper rash products, and their formulas differ in clear ways. DESITIN Maximum Strength Original Paste contains 40% zinc oxide in a base of petrolatum, cod liver oil and lanolin, and it lists fragrance. Era Organics Diaper Rash Cream contains 10% zinc oxide in a blend of plant oils and butters: plantain, calendula, comfrey, rosehip seed, aloe, jojoba, shea and cocoa butter. It is USDA Organic certified, cruelty-free and made in the USA, and it is fragrance-free. It is free from parabens, phthalates, sulfates, mineral oil, silicones, PEGs, talc, propylene glycol, drying alcohols and synthetic dyes. Era suits parents who want a certified organic, fragrance-free cream with a suggested minimum age of 0. DESITIN suits parents who want a 40% zinc oxide paste with a petrolatum base.

Ingredients side by side

DESITIN ingredient list as of 2026-10-10, from the DESITIN product page.

Key differences

USDA Organic certified

Era Organics Diaper Rash Cream is USDA Organic certified. DESITIN’s product page does not show USDA Organic, certified organic or Ecocert / COSMOS.

Fragrance-free vs. fragrance listed

Era is fragrance-free. DESITIN lists fragrance on its ingredient list. Parents who want to keep added scent away from a baby’s diaper area may prefer a fragrance-free formula.

Plant oils and butters vs. a petrolatum base

Era’s base is plant oils and butters with beeswax: plantain, calendula, comfrey, rosehip seed, aloe, jojoba, shea and cocoa butter. Era is also free from mineral oil and silicones. DESITIN’s base starts with petrolatum, cod liver oil and lanolin. Petrolatum does not appear on Era’s ingredient list.

Zinc oxide strength

Era contains 10% zinc oxide. DESITIN contains 40% zinc oxide. The two products are built differently: Era pairs its zinc oxide with a full blend of botanicals, while DESITIN’s paste is built around a higher zinc oxide percentage.

Cruelty-free and made in the USA

Era is cruelty-free and made in the USA. DESITIN’s product page does not show cruelty-free, Leaping Bunny or made in the USA.

Certifications and label claims

Which one should you choose?

  • You want certified organic ingredients: Era Organics Diaper Rash Cream is USDA Organic certified.
  • You want to avoid added fragrance: Era is fragrance-free. DESITIN lists fragrance.
  • You prefer plant oils and butters over petrolatum: Era’s base is plantain, calendula, comfrey, rosehip seed, aloe, jojoba, shea and cocoa butter.
  • You want a cream that starts at birth: Era’s suggested minimum age is 0, and it is made for newborns, babies and toddlers.
  • You want a 40% zinc oxide paste: DESITIN Maximum Strength Original Paste contains 40% zinc oxide, and its page describes the formula as hypoallergenic and pediatrician-tested.
Era Organics Diaper Rash Cream is USDA Organic certified, cruelty-free and made in the USA. It combines plantain, calendula, comfrey, rosehip seed, aloe, jojoba, shea and cocoa butter. It is fragrance-free and free from parabens, phthalates, mineral oil, silicones, talc and synthetic dyes. It comes in a recyclable 2 oz double-wall jar. Shop Era Organics Diaper Rash Cream.

Sources


Plain-text (Markdown) source: view on GitHub